{"id":4059,"date":"2026-01-27T22:02:22","date_gmt":"2026-01-27T20:02:22","guid":{"rendered":"https:\/\/life4hsp.com\/?p=4059"},"modified":"2026-01-27T22:02:22","modified_gmt":"2026-01-27T20:02:22","slug":"update-onderzoek-spg11-eerste-resultaten-veelbelovend","status":"publish","type":"post","link":"https:\/\/life4hsp.com\/it\/update-onderzoek-spg11-eerste-resultaten-veelbelovend\/","title":{"rendered":"Aggiornamento sulla ricerca SPG11 \u2013 I primi risultati sono promettenti"},"content":{"rendered":"

La ricerca su un possibile trattamento per la SPG11, condotta dal Paris Brain Institute<\/a>, \u00e8 iniziata nell\u2019aprile 2025 e procede secondo i piani. Si tratta di ricerca preclinica su modelli murini, finanziata da Euro-HSP<\/a> e Life4HSP.<\/a><\/p>\n

Lo studio valuta l\u2019efficacia e la sicurezza del farmaco venglustat. Le prime valutazioni nei topi indicano che il farmaco \u00e8 ben tollerato e suggeriscono un possibile miglioramento delle funzioni motorie e cognitive. Questi risultati sono cautamente incoraggianti e sono in linea con le evidenze di studi precedenti.<\/p>\n

Nel prossimo periodo, l\u2019attenzione sar\u00e0 rivolta alla prosecuzione della ricerca e alla raccolta di dati aggiuntivi. Tali dati sono fondamentali per confermare i risultati e valutare se siano possibili e responsabili ulteriori fasi di studio.<\/p>\n

Continueremo a monitorare attentamente i progressi e a tenervi informati sugli sviluppi futuri. Grazie al supporto dei donatori e dei partner, questa importante ricerca sulla SPG11 pu\u00f2 proseguire.<\/p>","protected":false},"excerpt":{"rendered":"

Het onderzoek naar een mogelijke behandeling voor SPG11, dat wordt uitgevoerd door het Paris Brain Institute, is gestart in april 2025 en verloopt volgens planning. Dit betreft preklinisch onderzoek in muismodellen en wordt gefinancierd door Euro-HSP en Life4HSP. Binnen het onderzoek wordt gekeken naar de werking en veiligheid van het medicijn venglustat. De eerste evaluaties […]<\/p>\n","protected":false},"author":6,"featured_media":4060,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[13],"tags":[],"class_list":["post-4059","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-onderzoek"],"acf":[],"yoast_head":"\nUpdate onderzoek SPG11 \u2013 eerste resultaten veelbelovend - Life4HSP<\/title>\n<meta name=\"description\" content=\"Preklinisch onderzoek naar een mogelijke behandeling voor SPG11 laat positieve eerste signalen zien. 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