{"id":4059,"date":"2026-01-27T22:02:22","date_gmt":"2026-01-27T20:02:22","guid":{"rendered":"https:\/\/life4hsp.com\/?p=4059"},"modified":"2026-01-27T22:02:22","modified_gmt":"2026-01-27T20:02:22","slug":"update-onderzoek-spg11-eerste-resultaten-veelbelovend","status":"publish","type":"post","link":"https:\/\/life4hsp.com\/de\/update-onderzoek-spg11-eerste-resultaten-veelbelovend\/","title":{"rendered":"Update zur SPG11-Forschung \u2013 Erste Ergebnisse vielversprechend"},"content":{"rendered":"<p data-start=\"189\" data-end=\"456\">Die Forschung zu einer m\u00f6glichen Behandlung der SPG11, die vom <a href=\"https:\/\/parisbraininstitute.org\/\">Paris Brain Institute<\/a>durchgef\u00fchrt wird, hat im April 2025 begonnen und verl\u00e4uft planm\u00e4\u00dfig. Es handelt sich um pr\u00e4klinische Forschung in Mausmodellen, finanziert durch <a href=\"https:\/\/www.eurohsp.eu\/\">Euro-HSP<\/a> und <a href=\"https:\/\/life4hsp.com\/de\/forschung-zur-behandlung-fur-spg11-gestartet\/\">Life4HSP.<\/a><\/p>\n<p data-start=\"458\" data-end=\"809\">Im Rahmen der Studie werden die Wirksamkeit und Sicherheit des Medikaments Venglustat untersucht. Erste Auswertungen bei M\u00e4usen zeigen, dass das Medikament gut vertragen wird und auf eine m\u00f6gliche Verbesserung der motorischen und kognitiven Funktionen hindeutet. Diese Ergebnisse sind vorsichtig ermutigend und stehen im Einklang mit fr\u00fcheren Forschungsergebnissen.<\/p>\n<p data-start=\"811\" data-end=\"1084\">In der kommenden Zeit liegt der Schwerpunkt auf der Fortsetzung der Forschung und der Sammlung zus\u00e4tzlicher Daten. Diese Daten sind entscheidend, um die Ergebnisse zu best\u00e4tigen und zu beurteilen, ob weitere Schritte in Richtung zus\u00e4tzlicher Studien m\u00f6glich und verantwortbar sind.<\/p>\n<p data-start=\"1086\" data-end=\"1282\">Wir werden den Fortschritt weiterhin aufmerksam verfolgen und Sie \u00fcber neue Entwicklungen informieren. Dank der Unterst\u00fctzung von Spendern und Partnern kann diese wichtige Forschung zur SPG11 fortgesetzt werden.<\/p>","protected":false},"excerpt":{"rendered":"<p>Het onderzoek naar een mogelijke behandeling voor SPG11, dat wordt uitgevoerd door het Paris Brain Institute, is gestart in april 2025 en verloopt volgens planning. Dit betreft preklinisch onderzoek in muismodellen en wordt gefinancierd door Euro-HSP en Life4HSP. Binnen het onderzoek wordt gekeken naar de werking en veiligheid van het medicijn venglustat. De eerste evaluaties [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":4060,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[13],"tags":[],"class_list":["post-4059","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-onderzoek"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Update onderzoek SPG11 \u2013 eerste resultaten veelbelovend - Life4HSP<\/title>\n<meta name=\"description\" content=\"Preklinisch onderzoek naar een mogelijke behandeling voor SPG11 laat positieve eerste signalen zien. 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